[{"data":1,"prerenderedAt":205},["ShallowReactive",2],{"DlFXI4Eibt_Bn9lrEZz1TYbHCWFZj3IvqwHQSEW-Exc":3,"N4UW3mQHRTEZieglehbksX3niEPcSZGZQUJwDnXlBek":194},{"code":4,"msg":5,"data":6},0,"",{"category":7,"tag":11,"hot":39,"new":78,"banner":118,"data":143,"cache":193},[8,9,10],"Agent","OpenAI","LLM",[12,14,17,20,23,25,27,30,33,36],{"title":8,"total":13},39,{"title":15,"total":16},"Google",44,{"title":18,"total":19},"Nvidia",13,{"title":21,"total":22},"Claude",11,{"title":9,"total":24},35,{"title":10,"total":26},85,{"title":28,"total":29},"DeepSeek",9,{"title":31,"total":32},"OCR",1,{"title":34,"total":35},"Chat",7,{"title":37,"total":38},"Generator",116,[40,48,55,64,71],{"id":41,"publish_date":42,"is_original":4,"collection":5,"cover_url":43,"cover_url_1_1":44,"title":45,"summary":46,"author":47},557,"2022-04-29","article_res/cover/7a9b1375ed9bb298154981bae42b794d.jpeg","article_res/cover/afa281dd52bc0454e6735daa8e6b0706.jpeg","Translation and summary of Messari Report [2.8 Kristin Smith, Blockchain Association and Katie Haun, a16z]","We need unity and speed right now.","Translation",{"id":49,"publish_date":50,"is_original":4,"collection":5,"cover_url":51,"cover_url_1_1":52,"title":53,"summary":54,"author":47},531,"2022-05-25","article_res/cover/e8362057f8fa189594c60afdfaaeb6e5.jpeg","article_res/cover/8ea08d0d6fa7eee6b57ed4ec61b61ad6.jpeg","Decentralized Society: Finding Web3’s Soul / Decentralized Society: Finding the Soul of Web3 -7","Decentralization through Pluralism When analyzing ecosystems, it's desirable to measure how decentralized it is.",{"id":56,"publish_date":57,"is_original":32,"collection":58,"cover_url":59,"cover_url_1_1":60,"title":61,"summary":62,"author":63},127,"2024-11-14","#Google #AI Game #World Model #AI Story","article_res/cover/0233a875b7ec2debf59779e311547569.jpeg","article_res/cover/6ffddb6ae4914b3c699493311aa9f198.jpeg","Google Launches \"Unbounded\": A Generative Infinite Character Life Simulation Game","Unbounded: A Generative Infinite Game of Character Life Simulation","Renee's Entrepreneurial Journey",{"id":13,"publish_date":65,"is_original":32,"collection":66,"cover_url":67,"cover_url_1_1":68,"title":69,"summary":70,"author":63},"2025-02-14","#Deep Dive into LLMs #Andrej Karpathy #LLM #Tool Use #Hallucination","article_res/cover/11e858ad6b74dfa80f923d549b62855c.jpeg","article_res/cover/615e1b320f1fc163edc1d2d154a6de33.jpeg","Andrej Karpathy's in-depth explanation of LLM (Part 4): Hallucinations","hallucinations, tool use, knowledge/working memory",{"id":72,"publish_date":73,"is_original":4,"collection":5,"cover_url":74,"cover_url_1_1":75,"title":76,"summary":77,"author":47},579,"2022-04-07","article_res/cover/39387376ba28447af1eb40576b9df215.jpeg","article_res/cover/02727ede8551ed49901d0abe6d6305b7.jpeg","Messari Report Translation and Summary 【1-7 Surviving the Winter】","I’d be more cautious here: 10 year and 10 hour thinking only.",[79,87,95,103,111],{"id":80,"publish_date":81,"is_original":32,"collection":82,"cover_url":83,"cover_url_1_1":84,"title":85,"summary":86,"author":63},627,"2025-03-20","#AI Avatar #AI Video Generation","article_res/cover/d95481358f73924989f8c4ee9c75d1c8.jpeg","article_res/cover/b74bc0fab01f8b6a6aa87696c0c3ed8b.jpeg","DisPose: Generating Animated Videos by Driving Video with Reference Images","DisPose is a controllable human image animation method that enhances video generation.",{"id":88,"publish_date":89,"is_original":32,"collection":90,"cover_url":91,"cover_url_1_1":92,"title":93,"summary":94,"author":63},626,"2025-03-21","#Deep Dive into LLMs #LLM #RL #Andrej Karpathy #AlphaGo","article_res/cover/446553a5c8f8f2f07d97b20eaee84e56.jpeg","article_res/cover/e6c2823409c9b34624064b9acbaca6f1.jpeg","AlphaGo and the Power of Reinforcement Learning - Andrej Karpathy's Deep Dive on LLMs (Part 9)","Simply learning from humans will never surpass human capabilities.",{"id":96,"publish_date":97,"is_original":32,"collection":98,"cover_url":99,"cover_url_1_1":100,"title":101,"summary":102,"author":63},625,"2025-03-22","#Deep Dive into LLMs #LLM #RL #RLHF #Andrej Karpathy","article_res/cover/8da81d38b1e5cf558a164710fd8a5389.jpeg","article_res/cover/96f028d76c362a99a0dd56389e8f7a9b.jpeg","Reinforcement Learning from Human Feedback (RLHF) - Andrej Karpathy's Deep Dive on LLMs (Part 10)","Fine-Tuning Language Models from Human Preferences",{"id":104,"publish_date":105,"is_original":32,"collection":106,"cover_url":107,"cover_url_1_1":108,"title":109,"summary":110,"author":63},624,"2025-03-23","#Deep Dive into LLMs #LLM #Andrej Karpathy #AI Agent #MMM","article_res/cover/a5e7c3d48bb09109684d6513287c661d.jpeg","article_res/cover/d3f22b7c0ab8d82fd2da457a299e0773.jpeg","The Future of Large Language Models - Andrej Karpathy's In-Depth Explanation of LLM (Part 11)","preview of things to come",{"id":112,"publish_date":105,"is_original":32,"collection":113,"cover_url":114,"cover_url_1_1":115,"title":116,"summary":117,"author":63},623,"#Google #Voe #AI Video Generation","article_res/cover/c44062fea0f336c2b96b3928292392c2.jpeg","article_res/cover/a041041c69092ad3db191c5bf3ff981b.jpeg","Trial of Google's video generation model VOE2","Our state-of-the-art video generation model",[119,127,135],{"id":120,"publish_date":121,"is_original":32,"collection":122,"cover_url":123,"cover_url_1_1":124,"title":125,"summary":126,"author":63},160,"2024-10-04","#Philosophy","article_res/cover/496990c49211e8b7f996b7d39c18168e.jpeg","article_res/cover/14dbaa1ade9cb4316d5829423a900362.jpeg","Time","The fungus of the morning does not know the waxing and waning of the moon, and the cicada does not know the seasons; this is a short life. To the south of the state of Chu there is a dark spirit which regards five hundred years as spring and five hundred years as autumn. In ancient times there was a great tree called the Ming which regarded eight thousand years as spring and eight thousand years as autumn; this is a long life.",{"id":128,"publish_date":129,"is_original":32,"collection":130,"cover_url":131,"cover_url_1_1":132,"title":133,"summary":134,"author":63},98,"2024-12-17","#AI Video Generator #Sora #Pika","article_res/cover/3b86e85d03fff4f356a3e4cf2bb329c9.jpeg","article_res/cover/5fa5c20ad0b40f8f544d257c0ef02938.jpeg","Pika 2.0 video generation officially released: effect comparison with Sora","今天，我们推出了Pika 2.0模型。卓越的文字对齐效果。惊人的视觉表现。还有✨场景成分✨",{"id":136,"publish_date":137,"is_original":32,"collection":138,"cover_url":139,"cover_url_1_1":140,"title":141,"summary":142,"author":63},71,"2025-01-14","#Nvidia #World Foundation Model #Cosmos #Physical AI #Embodied AI","article_res/cover/feddf8c832dfb45d28804291f6a42a9e.jpeg","article_res/cover/d6bc2f1186d96b78228c2283a17a3645.jpeg","NVIDIA's Cosmos World Model","Cosmos World Foundation Model Platform for Physical AI",[144,163,188],{"title":8,"items":145},[146,147,155],{"id":104,"publish_date":105,"is_original":32,"collection":106,"cover_url":107,"cover_url_1_1":108,"title":109,"summary":110,"author":63},{"id":148,"publish_date":149,"is_original":32,"collection":150,"cover_url":151,"cover_url_1_1":152,"title":153,"summary":154,"author":63},622,"2025-03-24","#OWL #AI Agent #MAS #MCP #CUA","article_res/cover/cb50ca7f2bf4d1ed50202d7406e1c19a.jpeg","article_res/cover/4aa7aa3badfacf3cc84121334f1050dd.jpeg","OWL: Multi-agent collaboration","OWL: Optimized Workforce Learning for General Multi-Agent Assistance in Real-World Task Automation",{"id":156,"publish_date":157,"is_original":32,"collection":158,"cover_url":159,"cover_url_1_1":160,"title":161,"summary":162,"author":63},620,"2025-03-26","#LLM #Google #Gemini #AI Agent","article_res/cover/53751a6dbbe990b1eb0b63f3b062aed4.jpeg","article_res/cover/031344981f0a212ff82d1f3a64aa5756.jpeg","Gemini 2.5 Pro, claimed to be far ahead of the competition, has been released with great fanfare: comprehensively surpassing other LLMs and topping the global rankings","Gemini 2.5: Our most intelligent AI model",{"title":9,"items":164},[165,172,180],{"id":166,"publish_date":157,"is_original":32,"collection":167,"cover_url":168,"cover_url_1_1":169,"title":170,"summary":171,"author":63},619,"#OpenAI #AI Image Generator #4o #MMM #AR Transformer","article_res/cover/2faffc97fcecf3151552cb0fd3206d89.jpeg","article_res/cover/1133cb4948af44cee2e7fbe79efb69e5.jpeg","The native image function of GPT-4o is officially launched","Introducing 4o Image Generation",{"id":173,"publish_date":174,"is_original":4,"collection":175,"cover_url":176,"cover_url_1_1":177,"title":178,"summary":179,"author":63},434,"2023-07-15","#Anthropic #OpenAI #Google #AI Code Generator #Claude","article_res/cover/e1b6f600a2b9f262a4392684e5f2ce25.jpeg","article_res/cover/6e1772e83f78f9a351ab23d3e414adee.jpeg","Latest Updates on Google Bard /Anthropic Claude2 / ChatGPT Code Interpreter","We want our models to use their programming skills to provide more natural interfaces to the basic functions of our computers.  \n - OpenAI",{"id":181,"publish_date":182,"is_original":4,"collection":183,"cover_url":184,"cover_url_1_1":185,"title":186,"summary":187,"author":63},417,"2023-08-24","#OpenAI","article_res/cover/bccf897d50a88b18364e35f7466387e0.jpeg","article_res/cover/2f871085c1073717c1703ae86e18056f.jpeg","The GPT-3.5 Turbo fine-tuning (fine-tuning function) has been released～","Developers can now bring their own data to customize GPT-3.5 Turbo for their use cases.",{"title":10,"items":189},[190,191,192],{"id":88,"publish_date":89,"is_original":32,"collection":90,"cover_url":91,"cover_url_1_1":92,"title":93,"summary":94,"author":63},{"id":96,"publish_date":97,"is_original":32,"collection":98,"cover_url":99,"cover_url_1_1":100,"title":101,"summary":102,"author":63},{"id":104,"publish_date":105,"is_original":32,"collection":106,"cover_url":107,"cover_url_1_1":108,"title":109,"summary":110,"author":63},true,{"code":4,"msg":5,"data":195},{"id":196,"publish_date":197,"is_original":32,"collection":198,"articles_id":199,"cover_url":200,"cover_url_1_1":201,"title":202,"summary":203,"author":63,"content":204},142,"2024-10-27","#Neuroscience","qsrvZXlkhJWMusOR7ZIE3Q","article_res/cover/4ae71aa1339e31dcb14b89119e7c2fb7.jpeg","article_res/cover/323090676fe29581705e3039f23cef63.jpeg","How memories are formed: Breaking DNA and repairing it","Memories are made by breaking DNA — and fixing it","\u003Cdiv class=\"rich_media_content js_underline_content\n                       autoTypeSetting24psection\n            \" id=\"js_content\">\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>. This discovery came from experiments on mice. When long-term memories are formed, some brain cells experience extremely strong electrical activity, so strong that it can cause breaks in DNA. Subsequently, an inflammatory response is triggered to repair this damage, helping to consolidate memories.\u003C/p>\u003Cp style=\"text-align: center;\">\u003Cimg class=\"rich_pages wxw-img js_insertlocalimg\" data-imgfileid=\"100007185\" data-ratio=\"0.6694444444444444\" data-s=\"300,640\" data-type=\"webp\" data-w=\"1080\" style=\"\" src=\"https://res.cooltool.vip/article_res/assets/17423781373130.7638514437364916.jpeg\">\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>I found some related comments quite amusing:\u003C/p>\u003Cblockquote style='margin-top: 20px;margin-bottom: 20px;;padding: 10px 10px 10px 20px;border-top: 3px none rgba(0, 0, 0, 0.4);border-right: 3px none rgba(0, 0, 0, 0.4);border-bottom: 3px none rgba(0, 0, 0, 0.4);border-left-color: rgba(0, 0, 0, 0.4);border-radius: 0px;background: none 0% 0% / auto no-repeat scroll padding-box border-box rgba(0, 0, 0, 0.05);width: auto;height: auto;box-shadow: rgba(0, 0, 0, 0) 0px 0px 0px 0px;overflow: auto;color: rgb(0, 0, 0);font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;font-size: 16px;letter-spacing: normal;text-align: left;'>\u003Cul style=\"margin-top: 8px;margin-bottom: 8px;;padding-left: 25px;\" class=\"list-paddingleft-1\">\u003Cli style=\";\">\u003Csection style=\";margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);line-height: 1.8em;letter-spacing: 0em;\">Now I understand why I couldn't memorize things when studying; turns out my genes were too strong.\u003C/section>\u003C/li>\u003Cli style=\";\">\u003Csection style=\";margin-top: 5px;margin-bottom: 5px;color: rgb(1, 1, 1);line-height: 1.8em;letter-spacing: 0em;\">My brain is self-protecting and doesn't want me to learn.\u003C/section>\u003C/li>\u003C/ul>\u003C/blockquote>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>, leading to the accumulation of errors in neuronal DNA.\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>For the first time linking DNA damage to memory, in 2021, Li-Huei Tsai, a neurobiologist at MIT in Cambridge, and her colleagues found that double-strand DNA breaks are common in the brain and linked them to the learning process.\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>To better understand the role of DNA breaks in memory formation, Radulovic and her team trained mice to associate mild electric shocks with a new environment. When placed back in that environment, the mice showed signs of \"remembering\" the experience, such as freezing in place and displaying fear. The researchers then analyzed gene activity in neurons within the hippocampus, a brain region closely associated with memory formation. They found that four days after training, a group of neurons showed higher activity in inflammation-related genes. However, three weeks after training, the activity of these genes had significantly decreased.\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>TLR9. TLR9 triggers an immune response to free-floating DNA fragments inside cells. Radulovic explained that this inflammatory response is similar to how immune cells defend against invading pathogens' genetic material. However, the study found that, in this case, nerve cells were not responding to external invaders but rather reacting to their own DNA.\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>The study revealed that TLR9 was most active in a small subset of neurons in the hippocampus, where DNA breaks were harder to repair. In these cells, DNA repair mechanisms gathered around an organelle called the centrosome, which is typically associated with cell division and differentiation. However, mature neurons do not divide, so Radulovic pointed out that the involvement of the centrosome in DNA repair was unexpected. She speculated that the mechanism of memory formation might resemble the adaptive process of immune cells when they encounter foreign substances. That is, during cycles of damage and repair, neurons may encode information about memory-forming events that trigger DNA breaks.\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>When researchers deleted the gene encoding the TLR9 protein in mice, these mice experienced difficulties in recalling long-term memories: when placed back in the environment where they had previously received shocks, they exhibited significantly less freezing behavior compared to mice with intact genes. Radulovic stated that these findings indicate\u003C/p>\u003Cp style='margin-bottom: 0px;;color: rgb(0, 0, 0);font-size: 16px;line-height: 1.8em;letter-spacing: normal;text-align: left;padding-top: 8px;padding-bottom: 8px;font-family: Optima, \"Microsoft YaHei\", PingFangSC-regular, serif;background-color: rgb(255, 255, 255);'>So can long-term memory be inherited?\u003C/p>\u003Cp style=\"display: none;\">\u003Cmp-style-type data-value=\"3\">\u003C/mp-style-type>\u003C/p>\u003C/div>",1752585446730]